Initial clinical experience of Stereotactic Body Radiation Therapy (SBRT) for liver metastases, primary liver malignancy, and pancreatic cancer with 4D-MRI based online adaptation and real-time MRI monitoring using a 1.5 Tesla MR-Linac.

Purpose/objectivesRecently a 1.5 Tesla MR Linac has been FDA approved and is commercially available.Clinical series describing treatment methods and outcomes for upper abdominal tumors using a 1.5 Tesla MR Linac are lacking.We present the first clinical series of upper abdominal tumors treated using a 1.5 Tesla MR Linac along with the acquisition o

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HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities

The exploitation of autophagy by some cancer entities to support survival and dodge death has been well-described.Though its role as a constitutive process is important in normal, healthy cells, in the milieu Plush Toys of malignantly transformed and highly proliferative cells, autophagy is critical for escaping metabolic and genetic stressors.In r

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